Joe, Carlo and Bobo are in their 60s. They have been friends since, in their twenties, they were part of a band: The Boys. After a successful album and a few more records their fame fades away. But the friendship and passion for music have survived everything, even a variety of personal events. Accompanied by Giacomo, younger than them, they continue to play, although they do other jobs. Suddenly, in their life - as Joe becomes a grandfather, Bobo is confronted with his young wife's maternity wishes and Joe has to deal with an illness - an incredible possibility breaks in: JD - a young and very famous trapper - wants to do a remake of their great success. Giacomo - who hides a secret - pushes Joe, Carlo and Bobo to overcome their perplexities, but it is necessary to solve a problem: they must find Anita, the splendid vocalist everyone was in love with and with whom they have lost track for 40 years. The Boys are on the road again, for a new adventure, with the same fun of their twentys.